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Macrocyclic lactones the macrocyclic lactones (avermectins and milbemycins) selectively paralyse parasites which are then pushed out of the gut lumen by peristalsis. Over-reactive unaffected responses include the hypersensitivities: B celland T cell-mediated protected responses designed to control pathogens, but that command to symptoms or medical complications. The emphasis of the database is on the pharmacological results of medicine and chemicals
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