Moreover, as reliable prevalence data needs to be provided to regulatory authorities to be able to obtain an orphan designation, elevated availability of such data for all uncommon diseases may symbolize an important preparatory step in facilitating orphan drug growth. Based on the experimental models and research in human beings, the next three patterns of glomerular deposits of immune complexes in numerous glomerular ailments have been observed: i) Exclusive mesangial deposits are characterised by very delicate form of glomerular illness. Viral antigens in tissue suspensions could also be detected by immunofluorescence, complement fixation, immunodiffusion and in tissue sections by immunoperoxidase staining
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