Essential position of monocytes and macrophages in the progression of acute pancreatitis. Historically, three specimens collected on alternate days inside a ten-day period must be examined; nonetheless, some could argue that one or two stool exams are adequate. Diagnosis could be confirmed by the presence of rimmed vacuoles in the muscle biopsy in combination with invasion of lymphocytes in nonnecrotic muscle fibers and interstitial infiltrates
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