Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration. The intermediate-danger group consisted of low-danger patients (underneath the age of 45) with excessive-threat tumour or high-risk patients with low-threat tumour. A recommendation (denoted by the numeral 1 after the rule of thumb assertion) signifies confidence that the advantages of the intervention clearly outweigh harms
medicine 54 357 methotrexate 2.5 mg on-line.