Rare cases present lesions suggestive encephalitis was frst reported in 2014 in six patients (two of demyelination and overlap with demyelinating syndromes male kids, one feminine teenager and three male adults)sixteen. This implies that there's a slender vary of safety between an effective dose and a lethal one. If prognosis is made in the neonatal interval, timing of surgery is between 3-6 months
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